Wen-Chun Hung Selected Research

tubocapsanolide A

1/2009	Tubocapsanolide A inhibits transforming growth factor-beta-activating kinase 1 to suppress NF-kappaB-induced CCR7.
5/2007	A bioactive withanolide Tubocapsanolide A inhibits proliferation of human lung cancer cells via repressing Skp2 expression.

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Wen-Chun Hung Research Topics

Disease

80	Neoplasms (Cancer) 01/2024 - 01/2002
27	Neoplasm Metastasis (Metastasis) 12/2022 - 11/2002
24	Carcinogenesis 01/2023 - 06/2003
22	Breast Neoplasms (Breast Cancer) 01/2023 - 09/2007
15	Lung Neoplasms (Lung Cancer) 06/2014 - 01/2002
14	Pancreatic Neoplasms (Pancreatic Cancer) 01/2024 - 06/2015
8	Lymphatic Metastasis 01/2021 - 10/2005
7	Urinary Bladder Neoplasms (Bladder Cancer) 03/2015 - 04/2007
6	Carcinoma (Carcinomatosis) 11/2020 - 11/2003
4	Primitive Neuroectodermal Tumors (PNET) 11/2022 - 11/2017
4	Colonic Neoplasms (Colon Cancer) 01/2022 - 08/2006
4	Adenocarcinoma 01/2019 - 03/2016
4	Hepatocellular Carcinoma (Hepatoma) 03/2013 - 01/2008
3	Infections 11/2013 - 01/2010
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 11/2011 - 02/2011
3	Nasopharyngeal Carcinoma 09/2008 - 10/2005
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2017 - 01/2016
2	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2017 - 11/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 02/2007 - 08/2003
1	Diabetes Mellitus 01/2023

Drug/Important Bio-Agent (IBA)

27	Proteins (Proteins, Gene)FDA Link 11/2022 - 01/2002
9	Matrix Metalloproteinases (MMPs)IBA 01/2019 - 11/2002
9	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 07/2014 - 11/2003
8	ArsenicIBA 07/2013 - 08/2007
7	EnzymesIBA 01/2023 - 01/2014
7	Small Interfering RNA (siRNA)IBA 01/2023 - 08/2005
6	CateninsIBA 02/2022 - 11/2011
6	Vascular Endothelial Growth Factor CIBA 01/2021 - 03/2013
6	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 08/2008 - 09/2002
5	Cysteine (L-Cysteine)FDA Link 01/2020 - 02/2007
5	MethyltransferasesIBA 01/2018 - 09/2006
5	Phosphotransferases (Kinase)IBA 11/2017 - 08/2005
5	CarcinogensIBA 07/2013 - 06/2003
5	Messenger RNA (mRNA)IBA 03/2011 - 01/2002
4	Gemcitabine FDA Link 01/2024 - 09/2016
4	S-Phase Kinase-Associated Proteins (Skp1 Protein)IBA 12/2022 - 02/2011
4	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2014
4	Cadherins (E-Cadherin)IBA 12/2015 - 12/2012
4	Matrix Metalloproteinase InhibitorsIBA 01/2015 - 11/2002
4	arseniteIBA 07/2013 - 11/2007
4	Transcription Factors (Transcription Factor)IBA 03/2013 - 09/2007
4	DNA (Deoxyribonucleic Acid)IBA 02/2012 - 09/2006
4	Glycoproteins (Glycoprotein)IBA 12/2008 - 06/2003
3	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2024 - 02/2010
3	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2024 - 07/2013
3	Protein-Arginine N-Methyltransferases (Methyltransferase, Protein Arginine)IBA 01/2023 - 12/2018
3	PhosphoenolpyruvateIBA 01/2023 - 01/2016
3	AntibodiesIBA 10/2022 - 04/2008
3	Cyclin-Dependent Kinases (cdk Proteins)IBA 02/2022 - 07/2006
3	LigandsIBA 01/2019 - 07/2008
3	Histones (Histone)IBA 05/2016 - 06/2004
3	Histone Deacetylase InhibitorsIBA 08/2013 - 06/2003
3	Matrix Metalloproteinase 2 (Gelatinase A)IBA 01/2009 - 09/2002
3	N- (2- cyclohexyloxy- 4- nitrophenyl)methanesulfonamideIBA 04/2008 - 11/2002
2	Peptides (Polypeptides)IBA 01/2024 - 06/2014
2	Glucose (Dextrose)FDA LinkGeneric 01/2023 - 12/2007
2	Estrogen ReceptorsIBA 01/2023 - 08/2003
2	TensinsIBA 11/2022 - 11/2017
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2022 - 11/2017
2	CytokinesIBA 10/2022 - 01/2021
2	Semaphorins (Semaphorin)IBA 02/2022 - 01/2022
2	Cyclin D1IBA 02/2022 - 04/2008
2	Lysine (L-Lysine)FDA Link 01/2021 - 05/2016
2	SialyltransferasesIBA 11/2020 - 05/2010
2	Biomarkers (Surrogate Marker)IBA 06/2019 - 01/2017
2	Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA 01/2019 - 06/2014
2	Pyruvate KinaseIBA 01/2018 - 01/2016
2	Argininosuccinate Synthase (Argininosuccinate Synthetase)IBA 12/2017 - 11/2013
2	Arginine (L-Arginine)FDA Link 12/2017 - 11/2013
2	Everolimus FDA Link 11/2017 - 11/2017
2	MTOR InhibitorsIBA 11/2017 - 11/2017
2	IntegrinsIBA 08/2016 - 05/2010
2	CC ChemokinesIBA 01/2015 - 01/2014
2	Protein Kinases (Protein Kinase)IBA 01/2015 - 04/2014
2	Dinoprostone (PGE2)FDA Link 07/2014 - 02/2013
2	indoleIBA 01/2014 - 01/2009
2	Histone Deacetylases (Histone Deacetylase)IBA 08/2013 - 03/2013
2	Vorinostat FDA Link 08/2013 - 03/2013
2	Drinking WaterIBA 07/2013 - 02/2011
2	Chemokine ReceptorsIBA 02/2013 - 01/2009
2	sodium arsenite (sodium metaarsenite)IBA 10/2012 - 11/2007
2	Hair DyesIBA 12/2011 - 04/2007
2	4- (N- methyl- N- nitrosamino)- 1- (3- pyridyl)- 1- butanoneIBA 05/2009 - 06/2003
2	LactonesIBA 01/2009 - 05/2007
2	WithanolidesIBA 01/2009 - 05/2007
2	tubocapsanolide AIBA 01/2009 - 05/2007
2	Transforming Growth Factor beta (TGF-beta)IBA 12/2007 - 12/2003
2	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 11/2007 - 11/2003
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2024
1	NeurotensinIBA 01/2024
1	Insulin (Novolin)FDA Link 01/2023
1	Mechanistic Target of Rapamycin Complex 1IBA 01/2023
1	plexinIBA 01/2023
1	Semaphorin-3AIBA 01/2023
1	Glutamine (L-Glutamine)FDA Link 01/2023
1	Neuropilin-2IBA 01/2023
1	TubulinIBA 01/2022

Therapy/Procedure

10	Therapeutics 04/2022 - 06/2003
3	Drug Therapy (Chemotherapy) 12/2022 - 09/2016
1	Radiotherapy 12/2022